《转基因生物安全与管理》主要由三部分组成。第一部分介绍了转基因技术的生物学基础,包括基因工程的原理、转基因技术的方法与发展、转基因生物及其产品对环境和健康的潜在风险,以及风险评估和风险管理的方法与内容;第二部分分析了转基因生物安全管理的政策、法规与制度体系,包括国际公约、部分国家的立法与管理经验,以及中国的相关法规制度与管理实践;第三部分阐述了转基因生物及其产品的社会一经济影响,包括转基因产品的标识、对国际贸易的影响、损害赔偿与补救、事故应急管理,以及公众意识与参与等。书中许多内容是基于作者多年从事转基因生物安全的研究工作和参加联合国相关公约国际谈判的经历,因此具有比较明确的观点。
《转基因生物安全与管理》可作为高等院校相关专业本科生和研究生学习转基因生物安全课程的教材,也可作为相关管理人员的培训教材和科研人员的参考书目。
Introduction
ChApter 1 MoleculAr BAsis of Genetic Engineering
1.1 The concept And structure of gene
1.2 DNA replicAtion
1.3 DNA trAnscription And its regulAtion
1.4 Post-trAnscription processing And regulAtion of RNA
1.5 Protein expression And its regulAtion
1.6 Restriction endonucleAse
ChApter 2 Principles And ApplicAtions of Genetic Engineering
2.1 ImportAnt events in the history of the development of recombinAtion DNA
2.2 IsolAtion of tArget genes
2.3 RecombinAnt
2.4 Vectors for genetic engineering
2.5 PlAnt trAnsformAtion methods
2.6 Methods of developing trAnsgenic AnimAls Introduction
ChApter 1 MoleculAr BAsis of Genetic Engineering
1.1 The concept And structure of gene
1.2 DNA replicAtion
1.3 DNA trAnscription And its regulAtion
1.4 Post-trAnscription processing And regulAtion of RNA
1.5 Protein expression And its regulAtion
1.6 Restriction endonucleAse
ChApter 2 Principles And ApplicAtions of Genetic Engineering
2.1 ImportAnt events in the history of the development of recombinAtion DNA
2.2 IsolAtion of tArget genes
2.3 RecombinAnt
2.4 Vectors for genetic engineering
2.5 PlAnt trAnsformAtion methods
2.6 Methods of developing trAnsgenic AnimAls
2.7 GenerAl process of GMO reseArch And development
ChApter 3 Development of TrAnsgenic Biotechnology
3.1 Development of trAnsgenic plAnts
3.2 Studies of trAnsgenic AnimAls
3.3 The reseArches on geneticAlly modi. ed microbes
3.4 Genetic engineering vAccine
ChApter 4 PotentiAl HeAlth Risks from GeneticAlly Modi. ed OrgAnisms
4.1 CommerciAl production stAtus of geneticAlly modi. ed food
4.2 The exposure of DNA
4.3 PotentiAl risks of GM food to heAlth
4.4 The scheme of risk Assessment of geneticAlly modi. ed food
ChApter 5 The PotentiAl EcologicAl Risk of GeneticAlly Modi. ed OrgAnisms
5.1 ImpAct of GMOs on the ecologicAl environment
5.2 HorizontAl gene .ow – biosAfety concern for recombinAnt DNA
5.3 VerticAl gene .ow - theoreticAl foundAtion of Alien gene escApe
ChApter 6 Risk Assessment of GMO: Methods And CAses
6.1 Principle And methods of geneticAlly modi.ed orgAnisms risk Assessment
6.2 Risk Assessment of the geneticAlly modi. ed crops 113
6.3 Risk Assessment of the geneticAlly modi.ed food crops
6.4 Risk Assessment of the geneticAlly modi. ed forests
6.5 Risk Assessment of the geneticAlly modi. ed microorgAnism
ChApter 7 Risk MAnAgement for GMOs
7.1 The de.nition, goAls And requirements of risk mAnAgement
7.2 The theoretic foundAtion on GMOs risk mAnAgement—Scienti. c UncertAinty
7.3 Principle of risk mAnAgement——PrecAutionAry principle
7.4 PrActice of GMOs mAnAgement——tAke EU As An exAmple
ChApter 8 Detection And Monitoring of TrAnsgenes
8.1 The signi.cAnce And necessity of detection And monitoring of trAnsgenes
8.2 Detective methods of trAnsgenes
8.3 Immunology AnAlysis of the proteins in GMOs
8.4 The detection method of trAnsgenic microorgAnisms
8.5 The uniform stAndArds of the GMO detection experiment
8.6 Environment monitoring of GMOs
ChApter 9 BiosAfety InternAtionAl LAw: CArtAgenA Protocol on BiosAfety
9.1 The bAckground of the Protocol
9.2 The bAsic principles of biosAfety protocol
9.3 MAin contents of biosAfety protocol
9.4 The negotiAtion progress After BiosAfety Protocol
ChApter 10 BiosAfety LegislAtions in Some Countries
10.1 BiosAfety legislAtion in EuropeAn Union
10.2 BiosAfety legislAtion in the United StAtes
10.3 BiosAfety legislAtion in JApAn
10.4 BiosAfety legislAtion in IndiA
10.5 BiosAfety legislAtion in BrAzil
10.6 BiosAfety legislAtion in AustrAliA
ChApter 11 FrAmework of ChinA’s BiosAfety Policies, RegulAtions And System
11.1 Policy frAmework of biosAfety in ChinA
11.2 Current lAws And regulAtions on GMO biosAfety in ChinA
11.3 MAnAgement system And implementAtion procedures of GMOs
ChApter 12 TrAnsboundAry Movements And LAbeling of Living Modi.ed OrgAnisms (LMOs)
12.1 MAin contents of trAnsboundAry movements of LMOs
12.2 NegotiAtion process of trAnsboundAry movements of LMOs in the Protocol
12.3 LAbeling requirements of LMOs And internAtionAl tendency
12.4 LAbeling of GMO in ChinA
ChApter 13 DAmAge LiAbility And Redress in BiosAfety LAw
13.1 Principles And mechAnisms of internAtionAl environmentAl dAmAges legislAtion
13.2 InternAtionAl negotiAtions on biosAfety dAmAge liAbility And redress
13.3 Proposed principles of internAtionAl biosAfety dAmAges legislAtion
13.4 Proposed mechAnisms in internAtionAl biosAfety dAmAges legislAtion
13.5 BiosAfety dAmAges legislAtion of some countries And regions
13.6 ChinA’s legislAtion on biosAfety dAmAges And its impActs
ChApter 14 Socio-Economic ImpActs of GMOs
14.1 Attention by the internAtionAl society to the socio-economic impActs of GM crops
14.2 Types of sociAl—economic impAct of GMOs
14.3 RelAtionship between BiosAfety Protocol And TWO
14.4 Possible ImpAct of SAfety MAnAgement on the InternAtionAl TrAde
ChApter 15 Emergency MAnAgement for BiosAfety
15.1 TheoreticAl AnAlysis
15.2 InternAtionAl lAw And the mAnAgement of GMOs
15.3 NAtionAl lAws
15.4 Emergency mAnAgement of GMOs sAfety in ChinA
15.5 Improvement of emergency mAnAgement of GMOs sAfety in ChinA
ChApter 16 Public EducAtion And PArticipAtion on BiosAfety 346
16.1 Requirements of internAtionAl environmentAl lAws And regulAtions
16.2 StAtus quo of public AwAreness on GMO biosAfety
16.3 NAtionAl lAws And regulAtions And requirements of public pArticipAtion
16.4 BArriers And demAnds of public pArticipAtion of biosAfety in ChinA
16.5 EstAblish mechAnism of public pArticipAtion in biosAfety
References